Quatre Winner & Dorothy Catalonia from the anime series Gundam Wing. Don’t go all “but she made a human shish-kabob out of him using a fencing epee!” on me. Bash them all you want, but they’ll always be one of my first and favorite OTP’s. :) I will freaking sink with this ship (hear that, Frozen Teardrop?).
Dream & Death from The Sandman graphic novels (wish the artist did her own version of Peanuts-style D&D instead of the real Linus and Lucy). I absolutely adore the original Dream and Death scene from the novels, where I learn there’s only one person—or entity—who can chuck a loaf of bread at the brooding Morpheus, King of Dreams whenever she wants. Gotta love the sibling relationship.
Glinda & Elphaba from the Wicked Years series by Gregory Maguire. This frienemy duo just bursts with all kinds of awesome, both in the book and in the musical.